Anybody got some absolute don't miss routes from New England to Lexington to do it in two days? I wish something like the Taconic went all the way!
x2 on picking up US 50 from Baltimore. Awesome roads, especially through West Virginia. The only change I would make is that once you reach Parkersburg, WV, you pick up WV Route 2 into Huntington, then take US 60 into Lexington.I-76/I-70 is a nice drive through the mountains... From NJ, I always take I-78 to I-81 to I-76/I-70, then staying on I-70 to I-71 and ultimately I-75 that takes you right into Lexington... It's not as nice as the Taconic, but it is not bad, and certainly much better than I-80 and above. However, if you really want a truly beautiful drive, and like switch backs, then drop all the way down south past Baltimore to US-50, and take that all the way out to Ohio, where you can eventually catch I-71/I-75 to Lexington. From downtown Baltimore I used to drive south to US 50 and then all the way out to Cincinnati, instead of taking the logical I-70 route. It's a little over 500 miles. Very doable in one day, and most enjoyable if you are really into driving through the country and remote areas... (Google has a satellite feature where you can actually see the road you would be driving in real life...)