Megasquirt controls the ON time for the injectors. Larger injectors get less ON time. You may get a little less resolution at low power/rpm but you may not notice it.
85 GTV6 3L
76 Suzuki GT500
2011 Jaguar XKR
A little government and a little luck are necessary in life, but only a fool trusts either of them. - P.J. O'Rourke